FREQUENTLY ASKED QUESTIONS
NO sorry, first and foremost all of our products are sold for RESEARCH PURPOSES ONLY and once again we are a supply company and research questions are beyond our scope of knowledge.
Most orders are processed and ship the same day. Orders placed after 12pm EST will ship the following day (excluding Sundays). Because we ship from within the USA, you can expect your package extremely fast no matter how you decide to pay.
We proudly use the United States Postal Service, www.usps.com. USPS has been extremely reliable and gives us the ability to ship to P.O. Boxes if need be.
If your country isn’t listed on our checkout page it’s because we do not offer service there. Currently we do not ship to Denmark, Germany, Norway, New Zealand, United Kingdom, India or The Philippines.
Give it a day or two for their system to update; it will show.
All packages are shipped from our central mailing facility in Colorado, USA.
Our business’s success relies upon you being satisfied and returning. Our products are made adhering to the strictest oversight and controls. We guarantee above 99% purity on all our products or we will happily replace your order free of charge!
We are a peptide chemical supply company.
Absolutely, we have a full customer support staff ready to take your calls from 9am to 9pm EST.
No. Our goal is to have every customer 100% satisfied, so we do offer a two day option. Our processing is so fast we don’t want to charge and exorbitant amount of money to our clients for shipping. Everything we do is to minimize your costs.
For health and safety reasons involving peptides we do not accept returns or refunds on products sold. We will however replace any product if it does not meet at least 99% Purity.
All of our peptides are stable at room temperature for approximately two years. However, once you reconstitute them we recommend storing them in the refrigerator.
Check your spam folder. Our system automatically generates a response stating we received your order as well as emails when your order is complete and with your tracking info.
There are endless arrays of information online for Melanotan II, we do not comment on anything regarding its alleged uses or how to administer this product. By purchasing from us you are agreeing you are qualified to handle these peptides and will NOT ingest them.
All of our products are proudly manufactured right here in the U.S.A.!
Sometimes if your order does not get processed you may have to clear your browser’s cache or change browsers. When you successfully click the “Process Order” button, a processing status bar will appear as your order is being sent to us. Normally orders are accepted within 30 seconds depending on your internet connection. If it takes longer than 2 minutes, you can contact us at [email protected] or at 1-888-995-1591 for assistance. We also have live chat directly on the site usually available from 9am-9pm (EST). Also, check your inbox and spam/junk folders to see if you received the confirmation email from us, it is sent automatically when a transaction is completed.
That is the normal color and consistency of the Sildenafil Citrate Liquid. Prior to using it in your experiments we recommend you vigorously shake the bottle each time you use it.
Absolutely not, however, if you are looking for white labeling we can provide basic labels with your company’s logo on them instead of ours. We can also provide generic labels with no logos. This service is included in all wholesale orders, please contact us as soon as you place your order so we can work with you to provide the proper label for your order. However, by law we must display the product name, potency, lot number, expiration, and proper warnings. If you do not contact us within 24 hours of placing your wholesale order, your products will ship with Peptide Pros’ labels on them.
Please keep in mind that the time frames for shipping displayed on checkout are ONLY estimates and we cannot guarantee delivery within that time. We process all orders within 24 hours, however, once an item leaves our facility, it is beyond our control. If there is a substantial delay, we will work with you to reach a fair resolution, usually a discount for future orders or a partial refund for shipping fees. These are handled case by case, but our customers are always satisfied with the remedy.
No. All of our Liquid Research Chemicals are stable at room temperature. We do however recommend that you refrigerate any peptides once they are reconstituted.
Lyophilized is a technical term for freeze dried. It is the state that our peptides are shipped and stored in. They do not need to be kept cold until reconstituted and are stable at room temperature for approximately two years in this state.
Absolutely, most of the time it will appear solid, however due to shipping and handling, the solid mass may break up and appear powdery. There is nothing wrong with this; it will not affect the purity of the peptide.
No, this is not a problem nor an indicator of good or bad quality. Simply give it a little time, it will dissolve completely. You can also roll the vial gently between your fingers, however NEVER shake the vial as this may damage the peptides.
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From your account page, you will be able to see any orders you’ve placed since signing up. If you placed an order prior to registering for a FREE account with PeptidePros.net, simply contact us and we will find it for you.
Just visit your account page and your total will be displayed there.
Simply contact us and we will make the necessary changes for you. If your order has already left and it has the wrong information on it, you will have to wait until the product is returned to us before we reship a replacement. We will cover the reship fee if it’s within the U.S.A., however, any international reship fees will be charged to the customer.
Absolutely not. We will not misrepresent any information on customs forms. Prior to purchasing, it is the buyers responsibility to know the taxes or VAT for importing items from the US into their country and they are responsible for any related fees.
If within the U.S.A. we offer FREE shipping on orders over $150.00. Any other delivery charges are calculated based on what you ordered, where it is being shipped, and how fast you require your order. Most domestic packages are under $10 and most international orders are around $40 (give or take). Enter in your address on the checkout page for your rates.
It is very common for customs to hold a parcel pending confirmation that the peptides are cleared to pass into your country. We provide a declaration with our orders so customs knows what they are and should allow them to pass. Please remain patient for your items, keep in mind this is something that is out of our control, however we will work with you until your parcel has been confirmed delivered.
Absolutely not! All of the products sold on PeptidePros.net are strictly for research purposes only. If you intentionally or accidentally ingest any products from Peptide Pros you are exposing yourself to severe medical risk. You should contact your health provider immediately. If you make any references or it is the belief of ANY of the staff at Peptide Pros that you intend to ingest our products, we will immediately cancel your order and ban you from ordering in the future. We will not under any circumstances discuss any potential effects any of our products would have if ingested, this would be ILLEGAL!
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It couldn’t be easier to use your Pros Points! As long as you’re signed into your account, you just add your items to your cart then on the checkout page, you’ll be given the option to redeem your points. It’s that easy!
Indeed they do, unlike our competition, there are no restrictions to redeeming your Pros Points.
You earn one Pros Point for every dollar you spend with Peptide Pros. Only ten Pros Points are needed to save a dollar! Check out all the details here.
After registering, you will receive one Pros Point for every dollar spent!
No problem, just contact us and we’ll credit your account for all of your previous orders.
There are two reasons why you didn’t earn points on your purchase:
If you redeemed your Pros Points to make a purchase, you do not earn Pros Points for that purchase.
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We use a third party company that hosts all of our reviews, you can not leave a review directly from our site. The ONLY way to leave a review on any of our products is through an email you receive after you’ve placed an order and received your product(s). All reviews are from verified customers so that you can be 100% sure the reviews on our site are real.
Due to the nature of some of our products and the varying laws around the world, we restrict shipping of certain items outside of the country. If a product is marked USA only, you will not be able to complete your order with the item in your cart if you live outside the USA.
The solubility of a peptide is figured out mostly by its polarity. Acidic peptides can be reconstituted in basic buffers, whereas basic peptides could be dissolved in acidic solutions. Hydrophobic peptides as well as neutral peptides which contain great deals of hydrophobic or polar uncharged amino acids should be liquefied in percentages of natural solvent such as DMSO, DMF, acetic acid, acetonitrile, methanol, propanol, or isopropanol, and after that watered down utilizing water. DMSO ought to not be utilized with peptides that methionine or free cysteine considering that it could corrode the side-chain.
Examine a section of the manufactured peptide just before dissolving the remainder of the sample. Lyophilized peptides should be centrifuged briefly to pellet all the material. You should check numerous different solvents until you locate the suitable one. Sonication could be made use of to enhance solubility.
First, assign a value of −1 to each acidic residue (Asp [D], Glu [E], and the C-terminal –COOH). After that, assign a value of +1 to each basic residue (Arg [R], Lys [K], His [H], and the N-terminal -NH2), and then calculate the overall charge of the peptide.
If the overall charge of the peptide is positive, the peptide is basic. Try to dissolve the peptide in distilled water if possible. If it fails to dissolve in water, then try to dissolve the peptide in a small amount of 10–25% acetic acid. If this fails, add TFA (10–50 µl) to solubilize the peptide, and then dilute it to your desired concentration.
If the overall charge of the peptide is negative, the peptide is acidic. Acidic peptides might be soluble in PBS (pH 7.4). If this fails, add a small amount of basic solvent such as 0.1 M ammonium bicarbonate to dissolve the peptide, and then add water to the desired concentration. Peptides that contain free cysteines should be dissolved in de-gassed acidic buffers because thiol moieties will be oxidized rapidly to disulfides at pH >7.
If the overall charge of the peptide is 0, the peptide is neutral. Neutral peptides usually dissolve in organic solvents. First, try to add a small amount of acetonitrile, methanol, or isopropanol. For very hydrophobic peptides, try to dissolve the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration. For Cys-containing peptides, use DMF instead of DMSO. For peptides that tend to aggregate, add 6 M guanidine, HCl, or 8 M urea, and then proceed with the necessary dilutions.
To prevent or minimize degradation, store the peptide in lyophilized form at −20°C, or preferably −80°C. If the peptide is in solution, freeze-thaw cycles should be avoided by freezing individual aliquots.
Positively charged residues: K, R, H, and the N-terminus
Negatively charged residues: D, E, and the C-terminus
Hydrophobic uncharged residues: F, I, L, M, V, W, and Y
Uncharged residues: G, A, S, T, C, N, Q, P, acetyl, and amide
RKDEFILGASRHD: (+5) + (-4) = +1 This is a basic peptide. See step #2 above.
EKDEFILGASEHR: (+4) + (-5) = -1 This is an acidic peptide. See step #3 above.
AKDEFILGASEHR: (+4) + (-4) = 0 This is a neutral peptide. See step #4 above.
Peptide purity is the quantity of the target peptide as identified by HPLC at 214 nm, where the peptide bond takes in. Water as well as recurring salts are not discovered by UV spectrophotometer. Various other impurities that can be located in the content consist of removal series (much shorter peptides lacking several amino acids of the target sequence), truncated sequences (created by capping actions to prevent the buildup of deletion peptides), and also incompletely deprotected series (produced throughout the synthesis or the last bosom process).
Peptide purity does not consist of any kind of water or salts in the sample. TFA arises from HPLC purification. The free N terminus and opposite chains such as Arg, Lys, as well as His kind trifluoroacetates and this permits percentages of TFA to contaminate the peptides. Peptides are typically delivered as trifluoroacetates having recurring water. Also in lyophilized peptides, varying amounts of noncovalently expecteded water still already existing.
All of Peptide Pros peptides are guaranteed to be 99% pure or better.
The net peptide content is different from the peptide pureness. The net peptide content is the portion of peptides about nonpeptidic products, mainly counterions and dampness. The web peptide content can be identified by amino acid evaluation. Usually, hydrophilic peptides absorb small quantities of dampness even under strict lyophilization problems. Net peptide material might differ from set to set depending upon the purification and also lyophilization processes.
We have strategic partnerships with various labs to produce only the highest purity peptides available. An example of the methods used are as follows:
Unlike the natural protein synthesis, peptides are manufactured from the C to N terminus. Peptide synthesis is done using PeptideSyn innovation based on Fmoc or t-Boc chemical make up to secure the alpha amino group. The deprotection representative (piperidine for Fmoc, TFA for Boc) releases the alpha amino team in planning for combining the following amino acid in the sequence. This exposes a new N-terminal amine to which the following amino acid could be triggered by among a number of reagents, developing a peptide bond. When the synthesis is total, peptides are cleaved from the material as well as de-protected. Peptides are then precipitated, cleaned, and lyophilized.
All products provided to Peptide Pros are taken into consideration the confidential home of the consumer. Peptide Pros provides totally free HPLC and also MS results with most orders. Peptides are purified by reverse-phase chromatography. The chromatogram suggests the number and also relative quantity of by-products. The molecular mass of the peptide is established by mass spectrometry to validate that the correct product is being delivered. MS outcomes additionally reveal the masses of the main contaminations. Net peptide material is indicated by either amino acid evaluation or elemental analysis. These methods permit the confirmation of the amino acid structure of the peptides. They work as additional ways of verification of peptide identity. All artificial peptides satisfying the customer’s purity requirements are sent. All residual elements, such as peptides not complying with the our pureness standards are discarded.
APIs also known as Active Pharmaceutical Ingredients are the substances in drugs that are pharmaceutically active, such as Tadalafil sildenafil, Clomiphene, and so on. Since our products are NOT intended for any pharmaceutical purposes and are sold strictly for research and development, our liquid research chemicals cannot be considered APIs. Although similar, their intended use is different and therefore are classified as research liquids.
Catalog peptides are commercially offered sequences. They are typically created in large quantities at high degrees of pureness. These peptides are normally customized to customers’ particular demands. For instance, specific sequences, alterations, pureness degrees, or lengths may be needed by the customer.
In recent years catalog peptides have grown in popularity as more and more research is being conducted and new discoveries are being made.
Peptide Pros offers a full line of catalog peptides.
Resin is the polymeric backbone to which substrates are secured. Various materials have various properties. For example, polystyrene swells in non-polar solvents, while polyethylene glycol swells in polar and non-polar solvents. Linkers are intermediate structures that attach the material to the substrate. Various linkers could be utilized to unmask different functional groups on the substrate.
Peptide purity is the term used to describe the percentage of peptide with the target sequence amongst the total amount of material. Due to the fact that peptide bond buildup is not 100 % efficient during peptide synthesis, not all polypeptide chains are made of the target sequence. As an example, some chains could not be full, or amino acids could not bind suitably. These deleted or incorrect sequences develop a particular percent of peptides in the majority of peptide combinations. We analyze as well as purify crude peptides utilizing reverse stage HPLC, and then assess the resulting product making use of MS to accomplish the desired target sequence purity.
After our peptides have been detoxified and also lyophilized, the white peptide powder will have some non-peptide components such as water, salts, absorbed solvents, as well as counter ions. The peptide content describes the real percentage weight of the peptide in your end product. This number varies, yet is generally 97 – 99 % depending on the pureness, sequence, as well as approaches utilized for synthesis as well as filtration. When calculating the concentration of peptide options for biological assays or various other experiments, it is vital that the peptide content is accounted for. The real peptide attention can be figured out by deducting the non-peptide weight from the complete weight, which permits you to determine just what quantity of solvent to make use of.
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