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Made in USA S-23 Liquid Research chemical bottle

What is SARMs S-23? Research Information

Product information

Other Names:

  • 1010396-29-8
  • CHEMBL512283
  • CCTH-methylpropionamide
  • UNII-XDK89456WM
  • S-23
  • S23 SARM
S-23 Chemical Structure

Discovery:

SARMs (selective androgen receptor modulators) belong to the androgen receptors ligands which tend to bind androgen receptors and display androgenic signaling (tissue-selective activation). There were initial efforts for the development of the SARMs based on testosterone molecule modifications in the decade of 1940s. S23 SARM is an investigational selective androgen receptor modulator (SARM) developed by GTX, Inc as a potential male hormonal contraceptive in rats.

Mechanism of action:

In the human body, bones and muscles contain androgen receptors. S-23 works on the mechanism of binding to the androgen receptors, which stimulates the changes in similarity to the stimulations by testosterone. These changes consist of muscle hypertrophy, fat loss, and increased bone density. When SARM binds to the androgen receptors, it tends to increase the activity of those genes, which make the muscle-forming proteins. These activated receptors send the signals for increasing the activity of cells for bone building. Different SARMS might have different degrees of selectivity.

Clinical applications:

Improved bone strength:

Hormones like oestrogen and testosterone are vital hormones for the maintenance of strong and healthy bones. Post-menopausal women tend to produce a very less quantity of oestrogen hormone which makes them vulnerable to different bone diseases specifically osteoporosis. When you are increasing the mineralization of bone, you also need to enhance the muscle mass to prevent fractures and speed up the recovery. S-23 offers unique benefits of health due to their dual action for both increasing muscle strength and activation of bone-building cells.

Increased lean muscle mass and decreased body fat:

According to research studies, S-23 helps in building lean muscle mass and decreasing the fat content in the body. The action of S23 may mimic the working of steroids, but it doesn’t produce any side effects in the body. In case of exceeding estrogen concentration in the body, it may cause a decrease in muscle mass. S23 SARM helps in countering the effects of estrogen on muscle mass loss. Similarly, glucocorticoids are the most used drugs for anti-inflammatory purposes, but their use can cause muscle loss. S23 can help in preserving the size, endurance, and power of both slow and fast-twitch muscle fibers after the long-term use of glucocorticoids.

Disclaimer

The information provided about SARM S23 in this section is only for research advancement and disbursement of knowledge. The material collected in this article is meant for informational purposes about SARM S23. It is not to be considered instructional in any way. Moreover, we have further empathized with this by making sure no dosage information of SARM S23 or recommendations about its way of consumption is mentioned. The information available in this article is a collection from different recognized studies and researches conducted by known experts and researchers in controlled medical facilities and institutions. Furthermore, the information provided in the article is not to encourage the reader to start its consumption or as an advertisement of the product. Administering any supplement or medication not FDA approved may be harmful and may cause serious illness.  Peptide Pros insist that none of their products be ingested under any circumstances.

References:

  • S-23 | Compound| Wikipedia| Link: https://en.wikipedia.org/wiki/S-23_(drug)
  • S-23 | DB07419| go.drugbank| https://go.drugbank.com/drugs/DB07419
  • S-23 | DB07419| Chemspider| http://www.chemspider.com/Chemical-Structure.24715019.html
  • Leaney, A. E., Beck, P., Biddle, S., Brown, P., Grace, P. B., Hudson, S. C., & Mawson, D. H. (2021). Analysis of supplements available to UK consumers purporting to contain selective androgen receptor modulators. Drug Testing and Analysis, 13(1), 122-127.
  • Jones, A., Chen, J., Hwang, D. J., Miller, D. D., & Dalton, J. T. (2009). Preclinical characterization of a (S)-N-(4-cyano-3-trifluoromethyl-phenyl)-3-(3-fluoro, 4-chlorophenoxy)-2-hydroxy-2-methyl-propanamide: a selective androgen receptor modulator for hormonal male contraception. Endocrinology, 150(1), 385-395.
  • Jones, A., Hwang, D. J., Narayanan, R., Miller, D. D., & Dalton, J. T. (2010). Effects of a novel selective androgen receptor modulator on dexamethasone-induced and hypogonadism-induced muscle atrophy. Endocrinology, 151(8), 3706-3719.

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