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What is SARMs S4 (Andarine) ? Research Information

Product information:

  • Molecular formula – C19H18F3N3O6
  • Molecular weight – 441.4 gmol-1
  • Half-life – 200 minutes
S4 SARMs Andarine Liquid chemical structure made in USA

Other names:

  • 3-(4-acetylaminophenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethylphenyl) propionamide andarine
  • Andarine (GTX-007)
  • S4 SARMS
  • GTx-007
  • 401900-40-1
  • S-4
  • 7UT2HAH49H
  • CHEMBL125236
  • SCHEMBL2689756
  • CHEBI:94760
  • BDBM18665
  • AOB5230
  • Propanamide, 3-(4-(acetylamino) phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3 (trifluoromethyl)phenyl)-, (2S)

Discovery of Andarine:

Andarine was discovered in the 1990s by Professor Dalton and his team at the University of Tennessee while attempting to develop prostate cancer treatment. It is an investigational selective androgen receptor modulator. Andarine is an orally active partial agonist of the androgen receptor. GTx Inc. (Nasdaq GTXI) holds the license for the development and commercialization of Andarine.

Mechanism of action:

S4 SARMS tend to attach to the proteins present in the body, known as androgen receptors. After the binding of andarine with these androgen receptors, these supplements direct the body muscles, bones, and other musculoskeletal structures to grow and develop. Unlike different other chemicals (which bind to these specific receptors as steroids), andarine does not cause side effects due to its mild and non-steroidal properties in any other part of the body.

Moreover, S4 SARMs also mimics the pharmacological and beneficial effects of the male hormone testosterone.

Clinical applications of SARMS S4 andarine:

Increased bone mineral density and muscle mass:

One of the most significant and popular benefits of S-4 SARMs is the increased muscle mass after consuming the supplement. According to an animal study, andarine is beneficial in restoring muscle strength and mass in animals. Moreover, the same dosage of andarine was also helpful in enhancing bone mineral density and muscle mass.

Most individuals can gain the required muscle mass of 5 lbs. in their one S4 cycle of the supplement. The simultaneous effects of andarine help in shredding the fat mass and gaining the lean muscle mass simultaneously. For the time being, andarine has its popularity for aesthetic and athletic purposes in the market. Most individuals use these supplements for their muscle gain and fat loss.

BPH (benign prostatic hyperplasia):

BPH is the non-cancerous increase in the prostate gland size. In the normal prostate gland, the 5-alpha-reductase type II enzyme helps metabolize the circulating testosterone into the DHT, which binds to the androgen-specific receptors in the nuclei of the cells. All of these events result in BPH. S4 SARMs provides an alternative approach for BPH suppression by reducing the detrimental effects of DHT and testosterone in the body.


The information provided about SARMS S4 Andarine in this section is only for the purpose of research advancement and disbursement of knowledge. The material collected in this article is meant for informational purposes about SARMS S4 and is not to be considered instructional in any way. Moreover, we have further empathized with this by making sure no dosage information of SARMS S4 or recommendations about its way of consumption are mentioned. The information available in this article is a collection from different recognized studies and researches conducted by known experts and researchers in controlled medical facilities and institutions. Furthermore, the information provided in the article is not to encourage the reader to start its consumption or as an advertisement of the product. Administering any supplement or medication not FDA approved may be harmful and may cause serious illness.  Peptide Pros insist that none of their products be ingested under any circumstances.


  • Andarine | C19H18F3N3O6| Pubchem |
  • Grata, Elia, et al. “SARM-S4 and metabolites detection in sports drug testing: a case report.” Forensic science international 213.1-3 (2011): 104-108.
  • Hansson, Annelie, et al. “Investigation of the selective androgen receptor modulators S1, S4 and S22 and their metabolites in equine plasma using high‐resolution mass spectrometry.” Rapid Communications in Mass Spectrometry 30.7 (2016): 833-842.
  • Ventura, Emiliano, et al. “Development and validation of a semi-quantitative ultra-high performance liquid chromatography-tandem mass spectrometry method for screening of selective androgen receptor modulators in urine.” Journal of Chromatography a 1600 (2019): 183-196.
  • Chen, Jiyun, Juhyun Kim, and James T. Dalton. “Discovery and therapeutic promise of selective androgen receptor modulators.” Molecular interventions 5.3 (2005): 173.
  • Bhasin, Shalender, and Ravi Jasuja. “Selective androgen receptor modulators (SARMs) as function promoting therapies.” Current opinion in clinical nutrition and metabolic care 12.3 (2009): 232.
  • Cawley, Adam T., et al. “Detection of the selective androgen receptor modulator andarine (S-4) in a routine equine blood doping control sample.” Drug Test Anal 8.2 (2016): 257-261.

Where to buy SARMS s4?

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