Product information:
- Molecular formula – C12H18Cl2N2O
- Molecular weight – 277.19
Other names:
- Planipart
- Clenbuterol
- Monores
- Clenbuterolum
- Clenbuterolum [INN-Latin]
- NAB 365
- 37148-27-9
- 1- (4-Amino-3,5-dichloro-phenyl)-2-tert-butylamino-ethanol
- CHEBI:174690
- dl-Clenbuterol
Discovery:
At first, in the late 1970s, clenbuterol was developed as a bronchodilator drug that helps expand the air passages of the lungs to cause the free flow of air through these tiny passages. These drugs helped treat patients who have asthma and other respiratory diseases. Later in the 1980s, scientists discovered that this drug could decrease body fat and increase muscle mass, which is beneficial for bodybuilders similar to anabolic steroids.
Mechanism of action:
Clenbuterol belongs to the beta-II adrenergic receptor agonists, which causes decreased airway obstruction and smooth bronchial muscle relaxation. This activation of the receptors (beta-2 adrenergic receptors) on adipose tissues and skeletal muscles is responsible for the lipolytic and anabolic properties of the clenbuterol drug. Liquid Clenbuterol has shown to stimulate both the central nervous system and the heart.
Results from various studies and trials utilizing clenbuterol also include:
- A more rapid loss of fat
- Increased excitability
- Increased energy production
- More determination
- Nervousness
Clinical applications:
Performance enhancement and weight loss:
According to clinical research clenbuterol has a potent association with reducing body fat and increasing muscle mass.
In animal studies, clenbuterol has evidence of prevention of muscle atrophy and increase of muscle growth. Moreover, this drug has been shown to increase the metabolism by utilizing the expense of fat as the main energy source and reduce its storage in the body.
Bronchodilation:
Clenbuterol is a potent beta-agonist (opposite of beta-blocker) that can act as a strong bronchodilator as well. These drugs are useful for lung disorders such as asthma, COPD (chronic obstructive pulmonary disease), lung infections, and emphysema. Clenbuterol increases the diameter of the narrowed passages and airways to accomplish smooth muscles relaxation. The mechanism of action of clenbuterol is similar to that of albuterol. However, the composition ad mechanism of clenbuterol makes it a long-acting beta-agonist drug.
Disclaimer:
The information provided about Clenbuterol in this section is only for the purpose of research advancement and disbursement of knowledge. The material collected in this article is meant for informational purposes and is not to be considered instructional in any way. Moreover, we have further empathized with this by making sure no dosage information of Clenbuterol or recommendations about its way of consumption are mentioned. The information available in this article is a collection from different recognized studies and researches conducted by known experts and researchers in controlled medical facilities and institutions. Furthermore, the information provided in the article is not to encourage the reader to start its consumption or as an advertisement of the product. Administering any supplement or medication not FDA approved may be harmful and may cause serious illness. Peptide Pros insist that none of their products be ingested under any circumstances.
References:
- Clenbuterol | C12H18Cl2N2O| Pubchem. (n.d.). Pubchem| https://pubchem.ncbi.nlm.nih.gov/compound/Clenbuterol
- Clenbuterol |Performance-enhancing drug|Wikipedia.com https://en.wikipedia.org/wiki/Clenbuterol
- Clenbuterol |DB01407|drugbank| https://go.drugbank.com/drugs/DB01407
- Ramos, Brian P., et al. “β2 adrenergic agonist, clenbuterol, enhances working memory performance in aging animals.” Neurobiology of aging 29.7 (2008): 1060-1069.
- Prather, IRVINE D., et al. “Clenbuterol: a substitute for anabolic steroids?.” Medicine and science in sports and exercise 27.8 (1995): 1118-1121.
- Barry, Arden R., and Michelle M. Graham. “Case report and review of clenbuterol cardiac toxicity.” Journal of cardiology cases 8.4 (2013): 131-133.
- Wheatley, David. “Clenbuterol (‘Spiropent’): A long-acting bronchodilator.” Current medical research and opinion 8.2 (1982): 113-119.
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